Take off any parts you don't want, but always do it after mid summer - late summer until mid Feb at the latest - these can 'bleed' like crazy in spring and summer if you cut them then.

Thank you very much!

Welcome to GoY.

I always reckon to prune a vine between leaf fall and January 1st. As Bamboo says, they bleed badly and the sap starts to rise very early in the year, even before signs of growth start

The stems will die back a way so give it a good trim to establish a framework after leaf fall. You may need to do more if the ends die back further in winter but don't cut growth after the buds start to swell in Spring. I cut mine back to a couple of buds from the main leaders.