A lot of the ornamental plants and shrubs in our garden are toxic, Nerium Oleander is extremely toxic. However, so long as you don't go eating any part of the shrub there isn't a problem. I would make sure that no small child was allowed near on their own unless I knew they were well enough trained not to pick bit of plants and put them in their mouth.

They are toxic to grazing animals.
Some peoples sensitive skins may react to the sap from them - i would class mine as sensitive and mine doesn't at all.

I have one of these in my front garden and have never had any problems of any kind.
It's worth knowing that a large number of common plants we have in our gardens are described as toxic !

I lost one last winter and a forum member kindly replaced it. I'll keep it in the GH next time.

Other precautions with Nerium: don't get the sap in open cuts, don't use it for barbeque skewers--you would be surprised what people do--and don't burn the wood--the smoke is toxic, too. Mostly no problem, as long as you treat it like any other non-edible plant!

Thank you all for your thoughts, I will glove and cover up when handling. I think I will put a small warning label/stick next to the plant. At present, my plan is to re-pot into 10" pots and place around the garden where suitable. Once again thank you all.

Keep an eye on the watering: Neriums are supposed to be drought tolerant, but that doesn't apply in pots. We have to give them a good soaking twice a day here, though every day or every other day is likelier in the UK.

Thanks Tugbrethil, As I understand it, we in the UK do not reach your temperatures. We are in a warm period by our standards and currently are at about 70 f to 75 f, so I have been watering about every two days. Plants appear to be doing ok so far.